Training in Transcranial Magnetic Stimulation: Experience from a Clinical and Research Centre

Lefaucheur JP, Aleman A, Baeken C, Benninger DH, Brunelin J, Di Lazzaro V, et al. Evidence‐based guide‐ lines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014‐2018). Clin Neurophysiol. 2020;131:474‐528. doi: 10.1016/j. clinph.2019.11.002. DOI: https://doi.org/10.1016/j.clinph.2020.02.003

O’Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, et al. Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry. 2007;62:1208‐16. doi: 10.1016/j.biopsych.2007.01.018. DOI: https://doi.org/10.1016/j.biopsych.2007.01.018

Blumberger DM, Vila‐Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, et al. Effectiveness of theta burst versus high‐frequency repetitive transcranial magnetic stimulation in patients with depression (THREE‐D): a randomised non‐inferiority trial. Lancet. 2018;391:1683‐92. doi: 10.1016/S0140‐ ‐6736(18)30295‐2. Erratum in: Lancet. 2018;391:e24. DOI: https://doi.org/10.1016/S0140-6736(18)30295-2

Clarke E, Clarke P, Gill S, Paterson T, Hahn L, Galletly C. Efficacy of repetitive transcranial magnetic stimulation in the treatment of depression with comorbid anxiety disorders. J Affect Disord. 2019;252:435‐9. doi: 10.1016/j.jad.2019.03.085. DOI: https://doi.org/10.1016/j.jad.2019.03.085

Carmi L, Tendler A, Bystritsky A, Hollander E, Blumberger DM, Daskalakis J, et al. Efficacy and safety of deep transcranial magnetic stimulation for obsessive‐compulsive disorder: a prospective multicenter randomized double‐blind placebo‐controlled trial. Am J Psychiatry. 2019;176:931‐8. doi: 10.1176/appi. focus.20103. DOI: https://doi.org/10.1176/appi.ajp.2019.18101180

Dinur‐Klein L, Dannon P, Hadar A, Rosenberg O, Roth Y, Kotler M, et al. Smoking cessation induced by deep repetitivetranscranialmagneticstimulationoftheprefrontal and insular cortices: a prospective, randomized controlled trial. Biol Psychiatry. 2014;76:742‐9. doi: 10.1016/j.biopsych.2014.05.020. DOI: https://doi.org/10.1016/j.biopsych.2014.05.020

Terraneo A, Leggio L, Saladini M, Ermani M, Bonci A, Gallimberti L. Transcranial magnetic stimulation of dorsolateral prefrontal cortex reduces cocaine use: A pilot study. Eur Neuropsychopharmacol. 2016;26:37‐ ‐44. doi: 10.1016/j.euroneuro.2015.11.011. DOI: https://doi.org/10.1016/j.euroneuro.2015.11.011

Rossi S, Antal A, Bestmann S, Bikson M, Brewer C, Brockmöller J, et al. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines. Clin Neurophysiol. 2021;132269‐ ‐306. doi: 10.1016/j.clinph.2020.10.003. DOI: https://doi.org/10.1016/j.clinph.2020.10.003

Fried PJ, Santarnecchi E, Antal A, Bartres‐Faz D, Bestmann S, Carpenter LL, et al. Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee. Clin Neurophysiol. 2021;132:819‐37. doi: 10.1016/j.clinph.2020.11.018. DOI: https://doi.org/10.1016/j.clinph.2020.11.018

Perera T, George MS, Grammer G, Janicak PG, Pascual‐Leone A, Wirecki TS. The Clinical TMS Society Consensus Review and Treatment Recommendations forTMSTherapyforMajorDepressiveDisorder.Brain Stimul. 2016;9:336‐46. doi: 10.1016/j.brs.2016.03.010. DOI: https://doi.org/10.1016/j.brs.2016.03.010

O’Reardon JP, Solvason HB, Janicak PG, Sampson S, Isenberg KE, Nahas Z, et al. Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: a multisite randomized controlled trial. Biol Psychiatry. 2007;62:1208‐16. DOI: https://doi.org/10.1016/j.biopsych.2007.01.018

Cotovio G, Ventura F, Rodrigues da Silva D, Pereira P, Oliveira‐Maia AJ. Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders. Brain Sci. 2023;13:1029. doi: 10.3390/brainsci13071029. DOI: https://doi.org/10.3390/brainsci13071029

Seybert C, Cotovio G, Grácio J, Oliveira‐Maia AJ. Future Perspectives From a Case Report of Transcranial Magnetic Stimulation, Cognitive Behavioral Therapy, and Psychopharmacological Treatment for Post‐traumatic Stress Disorder. Front Psychol. 2021;12:728130. doi: 10.3389/fpsyg.2021.728130. DOI: https://doi.org/10.3389/fpsyg.2021.728130

Senova S, Cotovio G, Pascual‐Leone A, Oliveira‐Maia AJ. Durability of antidepressant response to repetitive transcranial magnetic stimulation: Systematic review and meta‐analysis. Brain Stimul. 2019;12:119‐28. doi: 10.1016/j.brs.2018.10.001. DOI: https://doi.org/10.1016/j.brs.2018.10.001

Valiengo L, Maia A, Cotovio G, Gordon PC, Brunoni AR, Forlenza OV, et al. Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder in Older Adults: Systematic Review and Meta‐analysis. J Gerontol A Biol Sci Med Sci. 2022;77:851‐60. doi: 10.1093/gerona/glab235. DOI: https://doi.org/10.1093/gerona/glab235

Maia A, Almeida S, Cotovio G, da Silva DR, Viana FF, Grácio J, et al. Symptom provocation for treatment of obsessive‐compulsive disorder using transcranial magnetic stimulation: A step‐by‐step guide for professional training. Front Psychiatry. 2022;13:924370. doi: 10.3389/fpsyt.2022.924370. DOI: https://doi.org/10.3389/fpsyt.2022.924370

Oliveira‐Maia AJ, Garcia‐Guarniz AL, Sinanis A, Pascual‐Leone A, Press D. Comparative efficacy of repetitive transcranial magnetic stimulation for treatment of depression using 2 different stimulation devices: a retrospective open‐label study. J Clin Psychiatry. 2016;77:e743‐4. doi: 10.4088/JCP.15l10275. DOI: https://doi.org/10.4088/JCP.15l10275

Barahona‐Corrêa JB, Velosa A, Chainho A, Lopes R, Oliveira‐Maia AJ. Repetitive transcranial magnetic stimulation for treatment of autism spectrum disorder: a systematic review and meta‐analysis. Front Integr Neurosci. 2018;12:27. doi: 10.3389/fnint.2018.00027. DOI: https://doi.org/10.3389/fnint.2018.00027

Vacas SM, Stella F, Loureiro JC, Simões do Couto F, Oliveira‐Maia AJ, Forlenza OV. Noninvasive brain stimulation for behavioural and psychological symptoms of dementia: A systematic review and meta‐analysis. Int J Geriatr Psychiatry. 2019;34:1336‐45. doi: 10.1002/gps.5003. DOI: https://doi.org/10.1002/gps.5003

Cotovio G, Boes AD, Press DZ, Oliveira‐Maia AJ, Pascual‐Leone A. In older adults the antidepressant effect of repetitive transcranial magnetic stimulation is similar but occurs later than in younger adults. Front Aging Neurosci. 2022;14:919734. doi: 10.3389/ fnagi.2022.919734. DOI: https://doi.org/10.3389/fnagi.2022.919734

Cotovio G, Rodrigues da Silva D, Real Lage E, Seybert C, Oliveira‐Maia AJ. Hemispheric asymmetry of motor cortex excitability in mood disorders ‐ Evidence from a systematic review and meta‐analysis. Clin Neurophysiol. 2022;137:25‐37. doi: 10.1016/j. clinph.2022.01.137. DOI: https://doi.org/10.1016/j.clinph.2022.01.137

Rodrigues da Silva D, Maia A, Cotovio G, Oliveira J, Oliveira‐Maia AJ, Barahona‐Corrêa JB. Motor cortical inhibitory deficits in patients with obsessive‐compulsive disorder‐A systematic review and meta‐analysis of transcranial magnetic stimulation literature. Front Psychiatry. 2022;13:1050480. doi: 10.3389/fpsyt.2022.1050480. DOI: https://doi.org/10.3389/fpsyt.2022.1050480

Kelly MS, Oliveira‐Maia AJ, Bernstein M, Stern AP, Press DZ, Pascual‐Leone A, et al. Initial response to transcranial magnetic stimulation treatment for depression predicts subsequent response. J Neuropsychiatry Clin Neurosci. 2017;29:179‐82. doi: 10.1176/ appi.neuropsych.16100181. DOI: https://doi.org/10.1176/appi.neuropsych.16100181

Cotovio G, Oliveira‐Maia AJ, Paul C, Faro Viana F, Rodrigues da Silva D, Seybert C, et al. Day‐to‐day variability in motor threshold during rTMS treatment for depression: Clinical implications. Brain Stimul. 2021;14:1118‐25. doi: 10.1016/j.brs.2021.07.013. DOI: https://doi.org/10.1016/j.brs.2021.07.013

Cotovio G, Oliveira‐Maia AJ, Paul C, Viana FF, Rodri‐ gues da Silva D, Seybert C, et al. Reply: Variability in motor threshold. Brain Stimul. 2021;14:1523‐4. DOI: https://doi.org/10.1016/j.brs.2021.09.012

Oliveira‐Maia AJ, Press D, Pascual‐Leone A. Modula‐ tion of motor cortex excitability predicts antidepressant response to prefrontal cortex repetitive transcranial magnetic stimulation. Brain Stimul. 2017;10:787‐94. doi: 10.1016/j.brs.2017.03.013. DOI: https://doi.org/10.1016/j.brs.2017.03.013

Brem AK, Di Iorio R, Fried PJ, Oliveira‐Maia AJ, Marra C, Profice P, et al. Corticomotor Plasticity Pre‐ dicts Clinical Efficacy of Combined Neuromodulation and Cognitive Training in Alzheimer’s Disease. Front Aging Neurosci. 2020;12:200. doi: 10.3389/ fnagi.2020.00200 DOI: https://doi.org/10.3389/fnagi.2020.00200

Cotovio G, Seybert C, Silva D, Viana F, Pereira P, Oliveira‐Maia A. Motor cortex excitability modulation after intermittent theta burst stimulation: looking for stability and potential predictors of variability. Brain Stimul. 2023;16:309‐10. doi: 10.1016/j. brs.2023.01.566 DOI: https://doi.org/10.1016/j.brs.2023.01.566

Taylor J, Frandsen S, Anand A, Gunning F, Silbersweig D, Burdick K, et al. Deriving treatment targets for bipolar disorder: lesion network mapping across the valence spectrum. Brain Stimul. 2023;16:173‐4. doi: 10.1016/j.brs.2023.01.178 DOI: https://doi.org/10.1016/j.brs.2023.01.178

Viana F, Cotovio G, Silva D, Seybert C, Pereira P, Oliveira‐Maia A. The impact of normalization on motor evoked potential variability. Brain Stimul. 2023;16:311‐2. doi: 10.1016/j.brs.2023.01.572 DOI: https://doi.org/10.1016/j.brs.2023.01.572

Viana FF, Cotovio G, Silva D, Seybert C, Fonseca C, Matias R, et al. P.0894 Reducing between‐subject variability of motor evoked potential’s amplitude: neuronavigation vs normalization. Eur Neuropsychopharmacol. 2021;53:S656‐S7. DOI: https://doi.org/10.1016/j.euroneuro.2021.10.750

Taylor J, Frandsen S, Anand A, Gunning F, Silbersweig D, Burdick K, et al. Deriving Candidate TMS Targets for Bipolar Disorder with Brain Lesions Causing Mania or Depression. In: Neuropsychopharmacology ACo, editor. 61st Annual Meeting of the American College of Neuropsychopharmacology. 2022.

Oliveira‐Maia AJ. In Vivo Cortical Excitability Modulation in Major Depressive Disorder (PDM‐TMS). [accessed Jun 2022] Available from: https://clinicaltrials.gov/ct2/show/NCT054419692020.